Welcome to ITSI-Biosciences,LLC
Established in 2004, ITSI-Biosciences provide proteome and kinome analysis services, autoantibody profiling kits, recombinant proteins and ready-to-use kits for protein isolation and fractionation. We will help you identify autoantibodies associated with autoimmune diseases, sequence and map post translational modifications (PTMs) and discover/validate biomarkers. We use advanced mass spectrometers (LC/MS/MS), xMAP and 2D-DIGE technology, and validated protocols which ensure that your data is authentic, reproducible and publishable in high impact journals. We serve pharmaceutical companies, government research institutions including the NIH, USDA and FDA and universities.
Featured Projects & Promotions
- 11/12/2012- Identification of STAT2 serine 287 as a novel regulatory phosphorylation site in type I interferon-induced cellular responses
STAT2 is a positive modulator of the transcriptional response to type I interferons (IFNs). STAT2 acquires transcriptional function by becoming tyrosine phosphorylated and imported to the nucleus following type I IFN receptor activation. While most STAT proteins become dually ...
- 11/12/2012- PGPT™ & PGSP™ – kit for Plasma and Serum Proteomics to Prevent Ex-vivo Protease Activity
Plasma and serum proteomics is of interest because of the potential
Plasma and serum proteomics is of interest because of the potential presence of biomarkers for disease detection and prognosis. Sample preparation is a critical step in biomarker research and extreme care is needed to avoid or reduce pre-analytical and ex-vivo changes including enzymatic and non-enzymatic protein breakdown. Here we present the Proteomics Grade Tube that streamlines ...
- 10/01/2012- Modulation of hearing related proteins in the brain and inner ear following repeated blast exposures
Emerging studies show that blast exposure causes traumatic brain injury (TBI) and auditory dysfunction without rupture of tympanic membrane, suggesting central auditory processing impairment after blast exposure. There is limited information on the mechanisms of blast-induced TBI and associated peripheral and central auditory processing impairments. We utilized a repetitive blast ...